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<< Friday, May 03, 2013 >>


The Regulation of Fuel Metabolism and Substrate Availability During the Prolonged Fast of the Northern Elephant Seal: Dissertation defense by Jose Viscarra

Lecture/Seminar - Natural Sciences | May 3 | 1-2 p.m. | Science and Engineering Building 1, SE 370k


 5200 North Lake Rd, Merced, CA 95343

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Come and hear Jose Viscarra as he defends his disseration, "The Regulation of Fuel Metabolism and Substrate Availability During the Prolonged Fast of the Northern Elephant Seal."

Food deprivation in mammals results in profound changes in fuel metabolism and substrate regulation. Among these changes is a decreased reliance on the counter-regulatory dynamics by insulin-glucagon because of the reduced glucose utilization, and increased concentrations of lipid substrates in plasma to meet the energetic demands of peripheral tissues.

Prolonged food deprivation also increases lipid oxidation and utilization, which may contribute to the onset of insulin resistance associated with fasting. Because insulin resistance promotes the preservation of glucose and oxidation of fat, it has been suggested to be an adaptive response to food deprivation.


Professor Rudy Ortiz, rortiz@ucmerced.edu, 209-228-2964


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