University of California, Merced
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Parallel Lipoplex Folding Pathways Revealed Using Magnetic Tweezers
Tuesday, June 18 | 3-4 p.m. | S&E 300 Science and Engineering Building 1, 5200 North Lake Rd, Merced
Magnetic tweezers are a powerful tool in the investigation of single molecule DNA interaction with protein or polymer. Lipid-coated DNA nanoparticles (lipoplexes) are a potential gene delivery tool with promising therapeutic applications.
The mechanism of lipoplex assembly remains poorly understood. In this approach, we explored DNA packing by a cationic lipid DSTAP (distearoul trimethylammonium-propane). It showed that lipoplex folding occurs via two parallel pathways even at the single molecule level.
The progress through the two pathways can be monitored in real time using single DNA manipulations. The relative efficiency of the two pathways can be varied by external conditions.
Tax Services Now on Campus
March 19 – November 19, 2013 the third Tuesday of the month every month | 8:30-10:30 a.m. | K201 Kolligian Library, 5200 North Lake Rd, Merced
UC Merced Tax Services staff members are available on campus from 8:30 to 10:30 a.m. every third Tuesday of the month in K201.
The service is now being offered.
Drop in if you need assistance with campus-related tax questions and matters. Staff cannot offer specific tax advice, but can direct people to the appropriate resources.
Staff looks forward to serving you.
Monday, June 24 | Various, 5200 North Lake Rd., Merced
Summer session B runs from June 24 through Aug. 16.
Monday, July 8 | Various, 5200 North Lake Rd., Merced
Summer Session C runs from July 8 through Aug. 16.
University of California, Merced | 5200 North Lake Rd. Merced, CA 95343
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